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InsituPro VS
Links and References
InsituPro VS - Automated in situ Detection


Selected reference articles and useful resources for the InsituPro product line

References

Rainbow Trout Gonadal Masculinization Induced by Inhibition of Estrogen Synthesis Is More Physiological Than Masculinization Induced by Androgen Supplementation
Vizziano et al., Biology of reproduction 2008, in press

A role for Notch signalling in stromal survival and differentiation during prostate development
Orr et al., Endocrinology 2008. First published ahead of print September 18

Retinoic acid deficiency alters second heart field formation
Ryckebusch et al., PNAS 2008, 105(8): 2913–2918

Expression of the Lingo/LERN gene family during mouse embryogenesis
Haines and Rigby, Gene Expression Patterns 2008, 8 (2), 79-86

Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes
Filinaux et al., Dev. Biol. 2008, 320 (1) 60-71

Sox9 is required for prostate development
Thomsen et al., Dev Biol 2008, 316 (2), 302-311

Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology
Oginuma et al., Mech Dev 2008, 125 (5-6) 432-440

Histamine metabolism influences blood vessel branching in zebrafish reg6 mutants
Huang et al., BMC Developmental Biology 2008, 8:31

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development
Pispa et al., Human Molecular Genetics 2008, 17(21):3380-3391

Functional diversification of closely related ARF-GEFs in protein secretion and recycling
Richter et al., Nature 2007 448, 488-492

Wurst is essential for airway clearance and respiratory-tube size control
Behr et al., Nature Cell Biology 2007, 9(7):847-53.

BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration
Reddien et al., Development 2007, 134, 4043-4051

Wnt signals provide a timing mechanism for the FGF-retinoid differentiation switch during vertebrate body axis extension
Olivera-Martinez and Storey, Development 2007, 134, 2125-2135

Gene Duplication of the Zebrafish kit ligand and Partitioning of Melanocyte Development Functions to kit ligand a
Hultman et al., PLoS Genet 2007, 3(1): e17

Arabidopsis JAGGED LATERAL ORGANS Is Expressed in Boundaries and Coordinates KNOX and PIN Activity
Borghi et al., The Plant Cell 2007, 19:1795-1808

Expanded expression of Sonic Hedgehog in Astyanax cavefish: multiple consequences on forebrain development and evolution
Menuet et al., Development 2007, 134, 845-855

Regeneration and maintenance of the planarian midline is regulated by a slit orthologue
Cebria et al., Dev Biol 2007, 307 (2), 394-406

BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration
Reddien et al., Development 2007, 134, 4043-4051

Transcriptional profiling of inductive mesenchyme to identify molecules involved in prostate development and disease
Vanpoucke et al., Genome Biol. 2007, 8(10): R213

Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network
Jakobsen et al., Genes Dev. 2007 1; 21(19): 2448–2460.

Glycogen Synthase Kinase-3 Inactivation and Stabilization of  -Catenin Induce Nephron Differentiation in Isolated Mouse and Rat Kidney Mesenchymes
Kuure et al., J Am Soc Nephrol 2007, 18, 1130-1139

Interactions among PIN-FORMED and P-Glycoprotein Auxin Transporters in Arabidopsis
Blakeslee et al., Plant Cell. 2007, 19(1): 131–147

Morphogenesis defects are associated with abnormal nervous system regeneration following roboA RNAi in planarians
Cebria and Newmark, Development 2007, 134, 833-837

NOGO-A induction and localization during chick brain development indicate a role disparate from neurite outgrowth inhibition
Caltharp et al., BMC Developmental Biology 2007, 7:32

A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis
Warren et al., Genesis 2007, 45 (1) 51 – 58

Aristolochic Acid Induces Heart Failure in Zebrafish Embryos That is Mediated by Inflammation
Huang et al., Toxicological Sciences, 2007, 100(2), 486-494

Development of oral and pharyngeal teeth in the medaka (Oryzias latipes): comparison of morphology and expression of eve1 gene
Debiais-Thibaud et al., Journal of Experimental Zoology 2007, Part B, Molecular and Developmental Evolution Volume 308B (6), 693 – 708

In situ hybridisation techniques for mRNA detection in whole mount Arabidopsis samples
Hejatko et al., Nat. Protoc. 2006; 1(4): 1939-1946
"Our protocol was adopted for automation using an in situ dedicated robot "InsituPro" from INTAVIS. To create a program to perform the procedure according to our protocol is rather simple as the manufacturer provides instructions for very intuitive and user friendly programming of the automate. Using this robot [...] tissue permeabilisation, hybridisation and washing steps until detection [...] can be performed."

Dynamic and Compensatory Responses of Arabidopsis Shoot and Floral Meristems to CLV3 Signaling
Müller et al., The Plant Cell 2006, 18, 1188-1198

Protein and genomic organisation of vertebrate MyoR and Capsulin genes and their expression during avian development
Von Scheven et al., Gene Expr Patterns 2006, 6(4), 383-93

The TORNADO1 and TORNADO2 Genes Function in Several Patterning Processes during Early Leaf Development in Arabidopsis thaliana
Cnops et al., Plant Cell 2006, 18(4), 852–866.

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
Laurikkala et al., Development 2006, 133, 1553-1563

The molecular setup of the avian head mesoderm and its implication for craniofacial myogenesis
Bothe and Dietrich, Dev. Dynamics 2006; 235, 2845-2860

Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling
Ribes et al., Development 2006, 133, 351-361

ALCAM (CD166) Is a Surface Marker for Early Murine Cardiomyocytes
Hirata et al., Cells Tissues Organs 2006, 184:172-180

Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock
Shankaran et al. Dev Biol 2006, 304 (2), 615-632

Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis
Haines and Rigby, Gene Expression Patterns 2006, 7 (1-2), 23-29

her1 and her13.2 are jointly required for somitic border specification along the entire axis of the fish embryo
Sieger et al., 2006 Dev Biol 293 (1), 242-251

Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives
Wang et al., Dev Biol 2006, 297 (2), 433-445

Identification of a novel population of adrenal-like cells in the mammalian testis
Val et al., Dev Biol 2006, 299 (1) 250-256

Different Roles of Runx2 During Early Neural Crest–Derived Bone and Tooth Development
James et al., J Bone Miner Res 2006, 21:1034–1044.

Morphological and gene expression similarities suggest that the ascidian neural gland may be osmoregulatory and homologous to vertebrate peri-ventricular organs
Deyts et al., European Journal of Neuroscience 2006, 24 (8) 2299 – 2308

HAN11 binds mDia1 and controls GLI1 transcriptional activity
Morita et al., Journal of Dermatological Science 2006, 44 (1) 11-20

Comparative analysis of her genes during fish somitogenesis suggests a mouse/chick-like mode of oscillation in medaka
Gajewski et al., Dev Genes Evo 2006, 216 (6) 315-332

Large-scale expression screening by automated whole-mount in situ hybridization
Quiring et al., Mechanisms of Development 2004; 121(7-8), 971-976

Nonindependence of mammalian dental characters
Kangas et al., Nature 2004, 432, 211-214

The Claudin-like Megatrachea Is Essential in Septate Junctions for the Epithelial Barrier Function in Drosophila
Behr et al., Developmental Cell, 2003; 5, 611–620

Automated whole mount localisation techniques for plant seedlings
Friml et al., 2003, Plant Journal Volume 34 Issue 1, Pages 115 - 124

Automated in situ detection (AISD) of biomolecules
Plickert et al., Dev. Genes Evol 1997; 207, 362-367


Useful resources:

emap - The Edinburgh Mouse Atlas Project
A digital atlas of mouse development and database to be a resource for spatially mapped data such as in situ gene expression and cell lineage.

GEISHA - The Gallus gallus (chicken) EST and In Situ Hybridization Analysis database
A developing data base for chick ESTs and corresponding in situ images.

ZFIN - The zebrafish model organism database
A database containing everything starting from genes, ESTs, expression data up to the request for fish lines.

MEPD - Medaka Expression Patern Data Base
A database on in situ expression pattern of ESTs in the ricefish Medaka.

CK EST expression database of Flybase
The EST in situ expression database of flybase, a resource for Drosophila.

The gene expression database of TAIR
The gene expression resource of the TAIR Arabidopsis database. Please read their guidelines before linking or citing.

Xenopus express
Supplier of Pipid Frogs for laboratory research.




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